Possible side effects of Loxitane

Consumer Information (MedFacts)

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; dizziness; drowsiness; dry mouth; headache; nausea; stuffy nose; trouble sleeping; vomiting; weight gain or loss.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; altered mental abilities, including lack of response to your surroundings; chills or persistent sore throat; confusion; dark urine; decreased urination; fainting or faintness; fast or irregular heartbeat; hyperactivity; increased saliva production; increased thirst; involuntary, uncontrolled muscle movements; menstrual changes; mental or mood changes; muscle twitching; numbness or tingling of the skin; restlessness; seizures; shortness of breath; severe constipation; slurred speech; staggering or shuffling gait; stiff or rigid muscles; sweating; tremor; unexplained fever; vision changes; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

Advanced Consumer Information (Micromedex)

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

• uncontrollable movements of the mouth, tongue, cheeks, jaw, arms, or legs; or

• yellowing of your skin or eyes.

Other, less serious side effects may be more likely to occur. Continue to take loxapine and talk to your doctor if you experience

• dizziness or drowsiness,

• headache,

• weakness or tremor (shaking),

• agitation,

• an increased heart rate,

• constipation,

• dry mouth, or

• weight gain.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Consumer Information (Cerner Multum)

Along with its needed effects, loxapine can sometimes cause serious side effects. Tardive dyskinesia (a movement disorder) may occur and may not go away after you stop using the medicine. Signs of tardive dyskinesia include fine, worm-like movements of the tongue, or other uncontrolled movements of the mouth, tongue, cheeks, jaw, or arms and legs. Other serious but rare side effects may also occur. These include severe muscle stiffness, fever, unusual tiredness or weakness, fast heartbeat, difficult breathing, increased sweating, loss of bladder control, and seizures (neuroleptic malignant syndrome). You and your doctor should discuss the good this medicine will do as well as the risks of taking it .

Stop taking loxapine and get emergency help immediately if any of the following side effects occur:

Check with your doctor immediately if any of the following side effects occur:

Also, check with your doctor as soon as possible if any of the following side effects occur:

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

Certain side effects of this medicine may occur after you have stopped taking it. Check with your doctor as soon as possible if you notice any of the following effects after you have stopped taking loxapine:

Dizziness; nausea and vomiting; rapid or worm-like movements of the tongue; stomach upset or pain; trembling of fingers and hands; uncontrolled chewing movements

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.